Adenosine 3´:5´-cyclic monophosphate in relation to motility and senescence of spermatozoa
- 31 August 1973
- journal article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 184 (1074) , 109-114
- https://doi.org/10.1098/rspb.1973.0036
Abstract
Spermatozoa of the ram, bull, boar, stallion and cock contain 37 to 177 pmol cyclic AMP/109 cells. Slow cooling of spermatozoa followed by storage causes only a minor decrease but cold shock leads to a rapid and nearly total loss of cyclic AMP, some of which passes into the external medium. Fructose prevents the loss of cyclic AMP in anaerobically incubated spermatozoa. Motility and synthesis of cyclic AMP are abolished by fluoride, but both are restored after removal of fluoride by washing. Determinations of cyclic AMP represent a sensitive indicator of the onset of senescence changes in spermatozoa.Keywords
This publication has 10 references indexed in Scilit:
- Adenine Nucleotide Concentration and Redox Value of Human Spermatozoa1Biology of Reproduction, 1972
- Relation between the oxidation state of nicotinamide–adenine dinucleotide and the metabolism of spermatozoaBiochemical Journal, 1972
- NAD in the Metabolism of Motile SpermatozoaNature, 1971
- Stimulation and Maintenance of Ejaculated Bovine Spermatozoan Respiration and Motility by Caffeine1Biology of Reproduction, 1971
- Adenyl cyclase activity and cyclic 3′, 5′-AMP content of ejaculated monkey spermatozoaArchives of Biochemistry and Biophysics, 1971
- Effects of phosphodiesterase inhibitors and cyclic nucleotides on sperm respiration and motilityBiochemistry, 1971
- Enzymic control of fructolysis in primate spermatozoaBiochimica et Biophysica Acta (BBA) - General Subjects, 1971
- A simple and sensitive saturation assay method for the measurement of adenosine 3′:5′-cyclic monophosphateBiochemical Journal, 1971
- Studies on the metabolism of semenBiochemical Journal, 1946
- Studies on the metabolism of semenBiochemical Journal, 1945