A new synthesis of 2,2-dimethylchromenoquinolines from epoxides: synthesis of the alkaloid flindersine
- 1 January 1970
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society D: Chemical Communications
- No. 11,p. 666-667
- https://doi.org/10.1039/c29700000666
Abstract
Treatment of isopentenylquinoline epoxides with sodium hydroxide in dimethyl sulphoxide gave chromenoquinolines via allylic alcohol intermediates; this led to a new synthesis of the alkaloid, flindersine.Keywords
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