Improved preparation of (3.beta.,5.alpha.,14.alpha.)-3-hydroxy-14-methylcholest-7-en-15-one. Synthesis of ergostenone and 20.alpha.-(hydroxymethyl)pregnenone analogs

This publication has 12 references indexed in Scilit:

• 5 alpha-Cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of sterol biosynthesis, lowers serum cholesterol and alters distributions of cholesterol in lipoproteins in baboons.
  Proceedings of the National Academy of Sciences, 1982
• Inhibitors of sterol synthesis. Studies of in vitro effects of C27 15-oxygenated sterols on sterol synthesis in cell free homogenates of rat liver.
  Journal of Biological Chemistry, 1982
• 14 alpha-Ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol, a potent inhibitor of sterol biosynthesis, has two sites of action in cultured mammalian cells.
  Journal of Biological Chemistry, 1982
• Inhibitors of sterol synthesis. Chemical syntheses and activities of new derivatives of 15-oxygenated sterols
  Chemistry and Physics of Lipids, 1981
• 15-Oxygenated sterols by m-chloroperbenzoic acid oxidation of 3.beta.-acetoxy-5.alpha.-cholesta-8,14-diene
  The Journal of Organic Chemistry, 1981
• Inhibition of sterol biosynthesis in animal cells by 14 alpha-hydroxymethyl sterols.
  Journal of Lipid Research, 1980
• Inhibitors of sterol biosynthesis. Syntheses of 14α-alkyl substituted 15-oxygenated sterols
  Chemistry and Physics of Lipids, 1979
• Sterol synthesis. Chemical synthesis, structure determination and metabolism of 14?-methyl-5?-cholest-7-en-3?, 15?-diol and 14?-methyl-5?-cholest-7-en-3?, 15?-diol
  Chemistry and Physics of Lipids, 1978
• Sterol synthesis. Chemical synthesis of 3β-benzoyloxy -14α, 15α-epoxy-5α-cholest-7-ene, a key intermediate in the synthesis of 15-oxygenated sterols
  Chemistry and Physics of Lipids, 1977
• SYNTHESIS OF TRITIUM-LABELED 14ALPHA-METHYL-5ALPHA-CHOLEST-7-EN-3BETA-OL AND ITS ENZYMATIC DEMETHYLATION
  1966