Effect of tachycardia on cardiac output during normal and increased venous return

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Abstract
The effect of heart rate change on cardiac output was studied at various levels of right and left atrial pressure. At each atrial pressure, there was a different range of heart rate at which the cardiac output was maximal. As the atrial pressure increased, the heart rate range for maximal cardiac output shifted to a higher level. This tendency was enhanced during norepinephrine infusion.

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