Adrenal response to corticotropin during therapy with itraconazole
- 1 April 1987
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 31 (4) , 647-649
- https://doi.org/10.1128/aac.31.4.647
Abstract
Itraconazle is a triazole with a mechanism of action similar to that of ketoconazole. Endocrine side effects of ketoconazole, including impaired cortisol synthesis, have been well documented (A. Pont, J.R. Graybill, P.C. Craven, J.N. Galgiani, W.E. Dismukes, R.E. Reitz, and D.A. Stevens, Arch. Intern. Med. 144:2150-2153, 1984). We examined the adrenal response to corticotropin in 10 patients being treated with itraconazole. No impairment of cortisol synthesis could be demonstrated.This publication has 21 references indexed in Scilit:
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