Enantioselective synthesis of (S)-γ-acetylenic γ-aminobutyric acid (GABA) and (S)-trans-γ-butenynyl GABA
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 15,p. 1025-1027
- https://doi.org/10.1039/c39890001025
Abstract
The enantioselective syntheses of (S)-γ-acetylenic γ-aminobutyric acid (GABA)(1) and the (E)-butenynyl analogue (2) by phthalimide displacement of the homochiral prop-2-ynylic alcohols (6) and (11)[generated from the acetals (3) and (9), respectively], are reported.Keywords
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