STUDIES ON 3,7-DIMETHYL-l-(5-OXO-HEXYL)-XANTHINE (BL 191): THE INHIBITORY EFFECT OF BL 191 ON PDE IN VARIOUS TISSUES OF RATS
Open Access
- 31 December 1975
- journal article
- research article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 26 (1) , 117-120
- https://doi.org/10.1254/jjp.26.117
Abstract
BL 191 inhibited the activity of PDE [phosphodiesterase] from the cerebral cortex, fat pad and ileum non-competitively, while its inhibitory effect on heart muscle and liver PDE was competitive.This publication has 11 references indexed in Scilit:
- Studies on 3, 7-Dimethyl-1-(5-oxo-hexyl)-xanthine (BL 191). I. Cyclic 3', 5'-Nucleotide Phosphodiesterase (PDE) and the Inhibitory Effect of BL 191 on PDE in Rat Brain and HeartCHEMICAL & PHARMACEUTICAL BULLETIN, 1974
- Cyclic 3′,5′-nucleotide phosphodiesterase, IV. Two enzymes with different properties from brainBiochemical and Biophysical Research Communications, 1971
- Papaverine - induced inhibition of phosphodiesterase activity in various mammalian tissuesLife Sciences, 1971
- Some properties of cyclic 3′, 5′-nucleotide phosphodiesterase of mouse brain: effects of imidazole-4-acetic acid, chlorpromazine, cyclic 3′,5′-GMP, and other substancesBrain Research, 1970
- Presence of two 3′–5′-cyclic AMP phosphodiesterases in rat kidney and frog bladder epithelial cells extractsBiochemical and Biophysical Research Communications, 1970
- Cyclic 3′,5′-nucleotide phosphodiesterase: Preparation of a partially inactive enzyme and its subsequent stimulation by snake venonBiochimica et Biophysica Acta (BBA) - Enzymology, 1969
- Purification and Properties of 3',5'-Cyclic Nucleotide Phosphodiesterase from Dog Heart*Biochemistry, 1966
- Adenosine 3‘,5‘-Phosphate in Biological MaterialsJournal of Biological Chemistry, 1962