Monotone Smoothing with Application to Dose-Response Curves and the Assessment of Synergism

1 December 1990

journal article
Published by JSTOR

Vol. 46 (4) , 1071-85
https://doi.org/10.2307/2532449

Abstract

A spline-based procedure for monotone curve smoothing is proposed and is illustrated by application to dose-response curves. It is then shown how such smoothing...

Keywords

SMOOTHING
ANTAGONISM
DOSE RESPONSE
PROCEDURE
CURVES
SPLINE
MONOTONE
ILLUSTRATED
ASSESSMENT OF SYNERGISM

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