CAERULOMYCIN, A NEW ANTIBIOTIC FROM STREPTOMYCES CAERULEUS BALDACCI: I. PRODUCTION, ISOLATION, ASSAY, AND BIOLOGICAL PROPERTIES

1 August 1959

journal article
research article
Published by Canadian Science Publishing in Canadian Journal of Microbiology

Vol. 5 (4) , 317-321
https://doi.org/10.1139/m59-039

Abstract

Streptomyces caeruleus has been shown to produce a hitherto unknown antibiotic to which the name caerulomycin has been given. This was first obtained from a fresh isolate (PRL 1687), and subsequently, after the strain had been identified, from an authentic culture of S. caeruleus. It was extracted from culture filtrates with ether and purified as a colorless crystalline amphoteric substance, C12H11O2N3, which inhibited the growth of some filamentous fungi and yeasts and had weak activity against certain bacteria.

Keywords

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Analytical Chemistry, 1954
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