Molecular Encapsulation of Drugs by Cyclodextrins and Congeners

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Abstract
Complexes of metal ions with synthetic ligands have been for almost a century not only of academic interest but also a subject of many practical applications. In the field of biomedical sciences the formation of inorganic complexes has been extensively used for two purposes. In one type of application, inorganic complexes have been used to supply the organism with required metal ions. An example of such an application may be iron-dextran complexes which are used to supply iron in veterinary medicine. Another application of inorganic complexes has been in the detoxification of poisons. An example of this is BAL, British antilewisite, a mercaptane derivative used in the treatment of poisoning by lewisite, which is a poisonous arsene-containing gas used in World War I.

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