Bacterial infections in patients with chronic renal failure: occurrence with spinal cord injury

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Abstract
The available data were examined from 43 patients with spinal cord injuries and end-stage renal disease undergoing dialysis. All but 1 patient had a chronic urinary tract infection, which was characterized by persistence of the same organisms, for prolonged periods, high prevalence of mixed infections, scarcity of symptoms, lack of fever or leukocytosis and a considerable prevalence of cross-infection with the decubitus ulcers. Staphylococcus aureus and various gram-negative organisms were responsible for most of the vascular access infections in these patients. Decubitus ulcers were common and were frequently infected. Cross-contamination between infected decubitus ulcers, the urinary tract and vascular access seemed to have occurred on several occasions. The recorded respiratory infections were preponderantly caused by gram-negative organisms. Urinary tract, vascular access and decubitus infections seemed to be the source of septicemia in most of the recorded instances. Septicemia was the immediate cause of death in 1/2 of the patients.

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