Malaria Complicating Neoplastic Disease

Abstract
Two patients with neoplastic disease had transfusion-induced malaria. In a patient with acute myelogenous leukemia infected withPlasmodium vivax, neither his underlying disease nor intensive cytotoxic chemotherapy appeared to ameliorate or worsen the clinical course of his infection. In a splenectomized patient with metastatic carcinoma of the colon,P malariaeinfection was associated with a fulminant course simulating cerebral malaria. Despite delay in diagnosis, both patients responded dramatically to antimalarial chemotherapy and both developed appreciable antibody responses. (Arch Intern Med136:807-810, 1976)

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