The role of myocardial edema in the left ventricular diastolic stiffness
- 1 May 1976
- journal article
- research article
- Published by Springer Nature in Basic Research in Cardiology
- Vol. 71 (3) , 263-269
- https://doi.org/10.1007/bf01906451
Abstract
It has been shown that simultaneous administration of norepinephrine (10 μg/kg/min) and drotaverine (200 μg/kg/min) does induce interstitial myocardial edema which tends to increase left ventricular diastolic stiffness. These results suggest that in myocardial ischaemia temporary increase of left ventricular diastolic stiffness may be caused by interstitial edema. Es wurde bewiesen, daß die gleichzeitige, intravenöse Verabreichung von Noradrenalin (10 μg/kg/min) und Drotaverin (200 μg/kg/min) ein vorübergehendes interstitielles Myokardödem hervorruft, das zur diastolischen Erhöhung der linken Herzkammerwandsteifheit führt. Die Beobachtung läßt vermuten, daß die bei Myokardischämie zeitweilig in Erscheinung tretende, diastolische Erhöhung der linken Kammerwandsteifheit durch ein vorübergehendes, interstitiales Gewebsödem verursacht werden kann.Keywords
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