Purified Growth Hormone Releasing Factor Increases 45Ca Uptake into Pituitary Cells

1 June 1972

journal article
Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology

Vol. 50 (6) , 613-617
https://doi.org/10.1139/y72-091

Abstract

A purified extract of sheep hypothalamus possessing growth hormone releasing factor activity caused an increased uptake of ⁴⁵Ca from the incubation medium into the rat adenohypophysis concurrent with an increased release of growth hormone. The data are consistent with the "stimulussecretion coupling" model proposed for the release of preformed hormone from the adenohypophysis.

Keywords

MODEL
UPTAKE
GROWTH HORMONE
PITUITARY
INCUBATION
45CA
RELEASING FACTOR
PURIFIED
HORMONE RELEASING

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