Gradiental approach to neocortical functional organization
- 1 August 1989
- journal article
- research article
- Published by Taylor & Francis in Journal of Clinical and Experimental Neuropsychology
- Vol. 11 (4) , 489-517
- https://doi.org/10.1080/01688638908400909
Abstract
Examination of neuropsychological syndromes suggests strong congruence between neuroanatomical and functional neocortical metrics. Two cortical syndromes disrupt cognitively close functions if and only if their neuroanatomical territories are close. To capture this relationship, the concept of a cognitive gradient is introduced as a basic unit of macroscopic neocortical brain-behavioral analysis. A cognitive gradient is a continuous distribution of related functions along an axis defined at its extremes by a pair of sensory projection or motor areas. Cortical gradiental structure is viewed as a fundamental symmetric organization on which hemispheric elaborations are superimposed. The gradiental structure of the left hemisphere is presented in detail as an illumination of the concept. It is presumed that a similar set of elaborations can be uncovered for the right hemisphere. The gradiental model implies that at least from the macroscopic standpoint, functional neocortical organization is to a substantial degree continuous, interactive, and emergent, as opposed to mosaic, modular, and prededicated. It is proposed that a shift from latter to former properties signified a major development in the evolution of the brain. Thalamo-cortical integration may represent coexistence of evolutionally early and recent principles of cerebral organization.This publication has 57 references indexed in Scilit:
- Varieties of perseveration: A comparison of two taxonomiesJournal of Clinical and Experimental Neuropsychology, 1986
- Précis of The Modularity of MindBehavioral and Brain Sciences, 1985
- On the Basis for the Agrammatic's Difficulty in Producing Main VerbsCortex, 1984
- Contrasting Behavior of Right and Left Hemisphere-Damaged Patients on a Discriminative and a Semantic Task of Auditory RecognitionCortex, 1969
- Frequency, Picturability and Availability of Nouns in AphasiaCortex, 1969
- The Varieties of Naming ErrorsCortex, 1967
- Impaired Recognition of Meaningful Sounds in AphasiaCortex, 1966
- Perceptual Factors in the Pathogenesis of AnomiaCortex, 1966
- Specific Semantic Word Categories in AphasiaCortex, 1966
- DISCONNEXION SYNDROMES IN ANIMALS AND MANBrain, 1965