PRACTICAL AND THERAPEUTIC IMPLICATIONS OF CHLOROQUINE-INDUCED ITCHING IN TROPICAL AFRICA

  • 1 January 1977
    • journal article
    • research article
    • Vol. 6  (1) , 27-32
Abstract
The very uncomfortable itching following chloroquine chemotherapy of malaria in about 8% of the Nigeria population was examined. Six typical case reports are presented. Three stages in the course of the itching were identified and in the 2nd stage, 4 phases were outlined. The major implications of the pruritis are briefly discussed in respect to its effect on malaria treatment. Its possible link with more serious adverse effects and variations in drug metabolism are also mentioned. The treatment outlined is directed towards minimizing the intensity and duration of the itching reaction.

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