Concise stereoselective synthesis of (2S,4R)-4-hydroxyproline from (S)-O-benzylglycidol a novel cyclization
- 1 January 1988
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 23,p. 1527-1528
- https://doi.org/10.1039/c39880001527
Abstract
An efficient stereoselective route to (2S,4R)-4-hydroxyproline from (S)-O-benzylglycidol has been established via a novel iodine-mediated cyclization of the N-benzoyl-γ,δ-unsaturated amide.Keywords
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