Synthesis of Water Soluble Undecagold Clusters for Specific Labelling of Proteins
Open Access
- 1 October 1989
- journal article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 44 (10) , 1313-1322
- https://doi.org/10.1515/znb-1989-1027
Abstract
A highly water soluble undecagold cluster was prepared using a N-hydroxyethyl-N-acetyl-derivative of 4,4′,4″-phosphinidynetri(benzenemethanamine). Monofunctional clusters were synthesized in high yield by the exchange of ligands with phosphines having one free amino group. The clusters can be used for heavy atom labelling of proteins after introduction of a reactive maleimido group.Keywords
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