Pertussis vaccine oedema: An experimental model for the action of penicillamine-like drugs
- 1 August 1976
- journal article
- research article
- Published by Springer Nature in Inflammation Research
- Vol. 6 (5) , 613-617
- https://doi.org/10.1007/bf01971579
Abstract
A delayed hypersensitivity response was induced in the rat paw using pertussis vaccine. Oedema was measured after the challenging injection.d-Penicillamine and levamisole enhanced the response, while indomethacin suppressed it. This model is useful to distinguish the effects of antiinflammatory drugs from those liked-penicillamine which have a specific activity in rheumatoid arthritis.This publication has 8 references indexed in Scilit:
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