Parasitological and immunological aspects ofTrypanosoma cruzi infection in nude rats
- 1 January 1983
- journal article
- research article
- Published by Springer Nature in Zeitschrift Fur Parasitenkunde-Parasitology Research
- Vol. 69 (2) , 141-147
- https://doi.org/10.1007/bf00926950
Abstract
The role of the thymus on immunity of rats againstTrypanosoma cruzi infection was investigated in vivo. The athymic (nu/nu) rats were shown to be significantly more susceptible to the acute phase of the infection than the control nu/+ rats, as measured by increased parasitemia and mortality. Specific anti-T. cruzi antibodies, complement, IgM and IgG2a serum levels were determined. The results would indicate the essential role of antibodies in immunity to acute Chagas' disease through T-dependent immune response.This publication has 23 references indexed in Scilit:
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