SEASONAL-CHANGES IN THE VALUES OF BLOOD-COAGULATION AND ANTICOAGULATION SYSTEMS IN MALES IN THE PRE-CLINICAL STAGE OF ISCHEMIC-HEART-DISEASE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 20  (3) , 61-64
Abstract
Males (52) (aged 23-40 yr) were examined in the preclinical stage of ischemic heart disease revealed seasonal differences in the values of the blood coagulation and anticoagulation systems: in the spring, there was an increase in blood coagulation activity displayed by growth of the concentration of fibrinogen and soluble fibrin and a reduction in the amount of the plasminogen activator. Preventive treatment of patients in the spring, the most unfavorable season in respect to the effect of the pathogenetic factors, is suggested.