THE BIOLOGIC EFFECTS OF THYMUS EXTRACT (HANSON)

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Abstract
In this investigation we believe that we have learned something suggestive concerning the thymus gland and what is equally important, perhaps, we have evolved a novel procedure for the study of this and possibly other endocrine products. Following the continuous administration of thymus extract to successive generations of parents, marked acceleration in the rate of growth and development has been observed during the early life of the offspring, particularly of the third and later generations. Thus the rate of development encountered in the fifth generation of young rats born of four generations of thymus treated forebears is almost beyond belief. METHODS OF EXPERIMENTAL PROCEDURE A colony of twelve white rats was secured from the Wistar Institute, June 16, 1933. These were divided into test and control groups. The test animals have been subjected to date to the intraperitoneal injection of 1 cc. of thymus extract (Hanson) daily, even during the

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