Osteogenesis imperfecta and hyperplastic callus formation: Light‐ and electron‐microscopic findings

Abstract
In rare cases of osteogenesis imperfecta, an “overshoot” growth of new bone may occur, which, clinically gives the impression of a tumour. This condition is known as hyperplastic callus formation. Morphology showed an excessive mixed desmal-chondral osteoneogenesis. Atypical collagen fibrils in non-callus tissue represent an indicator for this callus formation in individual patients.

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