Abstract
Antibody ResponseVariation in the streptococcal immune response related to the site of infection (Tables 1 and 4) is supported by a growing body of information with pervasive implications, both practical and theoretical. The report of Burnett20 contains perhaps the first observations that certainly in retrospect can be interpreted as a warning not to rely on the antistreptolysin-O (ASO) test to exclude a streptococcal etiology in pyoderma. A mild immune response was also postulated lor streptococcal pyoderma on the basis of ASO findings by Markowitz et al.29 Interpretation of the ASO levels in these two studies was hampered by the . . .