Synthesis and in vitro activity of a new carbapenem, RS-533.
- 1 January 1983
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 36 (8) , 1034-1039
- https://doi.org/10.7164/antibiotics.36.1034
Abstract
The synthesis and in vitro antimicrobial activity of a new synthetic carbapenem, (5R, 6S)-6-[(R)-1-hydroxyethyl]-2-[(S)-l-acetimidoylpyrrolidin-3-ylthio]-l-carbapen-2-em-3-carboxylic acid (RS-533), are described. The MIC values of related penems and carbapenems are also given for comparison with those of the new carbapenem.This publication has 2 references indexed in Scilit:
- Thienamycin, a new .BETA.-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.The Journal of Antibiotics, 1979
- In Vitro Activity of ThienamycinAntimicrobial Agents and Chemotherapy, 1978