Conformational Relationships Between Analogs of Acetylcholine and Those of Local Anesthetics in Solution
- 1 November 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (11) , 3416-3419
- https://doi.org/10.1073/pnas.69.11.3416
Abstract
Conformations of analogs of acetylcholine and of related local anesthetics, in which either of the oxygen atoms had been replaced by other heteroatoms, were studied in solution by nuclear magnetic resonance. Several correlations between structure and conformation could be made.Keywords
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