TC-99M HMDP (HYDROXYMETHYLENE DIPHOSPHONATE) - A RADIOPHARMACEUTICAL FOR SKELETAL AND ACUTE MYOCARDIAL INFARCT IMAGING .2. COMPARISON OF TC-99M HYDROXYMETHYLENE DIPHOSPHONATE (HMDP) WITH OTHER TECHNETIUM-LABELED BONE-IMAGING AGENTS IN A CANINE MODEL

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 21  (10) , 967-970
Abstract
99mTc hydroxymethylene diphosphonate (Tc-HMDP) was compared with the 2 other diphosphonates (Tc-MDP [methylene diphosphonate] and Tc-HEDP [(1-hydroxyethylidene) diphosphonate]) and 99mTc pyrophosphate (Tc-PPi) in a canine model of acute myocardial infarction. The Tc-HMDP showed higher uptake in infarcted myocardium than the other 2 diphosphonates and uptake equivalent to that of Tc-PPi.