Opiate pharmacology and individual differences. I. Psychophysical pain measurements
- 1 June 1981
- journal article
- Published by Wolters Kluwer Health in Pain
- Vol. 10 (3) , 357-366
- https://doi.org/10.1016/0304-3959(81)90097-x
Abstract
A new electric stimulation pain assessment technique using the Tursky electrode and a non-parametric analysis of subjects ratings was found sensitive to aspirin, morphine and opiate antagonists in a series of double-blind cross-over trials in normal adults. Stable individual differences in pain sensitivity (off medication) were maintained on two testing sessions 7 months apart. Older individuals were less pain sensitive than younger individuals. Men were more insensitive than women under age 30. Together, these results suggest the empiric usefulness of this pain measurement technique.Keywords
This publication has 22 references indexed in Scilit:
- Analgesia to painful stimuli in affective illnessAmerican Journal of Psychiatry, 1979
- Analgesia to pain stimuli in schizophrenics and its reversal by naltrexonePsychiatry Research, 1979
- β-Endorphin-Like Immunoreactivity in Cerebrospinal Fluid and Plasma of Patients with Schizophrenia and Other Neuropsychiatric DisordersPharmacopsychiatry, 1979
- Naloxone alters pain perception and somatosensory evoked potentials in normal subjectsNature, 1977
- The influence of anxiety and pain sensitivity on experimental pain in manPain, 1977
- A model to evaluate mild analgesics in oral surgery outpatientsClinical Pharmacology & Therapeutics, 1976
- Effects of suggestion on d' and Cx for pain detection and pain tolerance.Journal of Abnormal Psychology, 1974
- Analgesic Strength of 33 Percent Nitrous Oxide: A Signal Detection Theory EvaluationScience, 1973
- Signal detection theory procedures are not equivalent when thermal stimuli are judged.Journal of Experimental Psychology, 1973
- Sensory-decision theory analysis of the placebo effect on the criterion for pain and thermal sensitivity (d').Journal of Abnormal Psychology, 1969