Serum Cholesterol, High-density Lipoprotein Cholesterol and Five-year Survival in Elderly People

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Abstract
In the year 1982 serum cholesterol and high-density hpoprotein (HDL) cholesterol were measured in 535 people aged 85 years participating in a health survey screening. All subjects were living at home. During the 5-year follow-up, 186 (34.8%) of the subjects died. There was a J-shaped relation between serum cholesterol and mortality. Mortality was lowest at serum cholesterol 5.0–5.9 mmol/1 for men and 7.0–7.9 mmol/1 for women. The greatest mortality was observed in men with cholesterol ≥6.0 mmol/1 and in women with cholesterol ≥8.0 mmol/1. There was a significant negative association of serum HDL cholesterol with mortality. Mortality was highest (53.3%)in men with serum HDL cholesterol < 0.80 mmol/1. Mortality was low (16.5%) in women with serum HDL cholesterol > 1.8 mmol/1.