Effect of Non-toxic Concentrations of Acriflavine on Unscheduled DNA-synthesis and Survival of Synchronized HeLa Cells Exposed to Ultra-violet Light
- 1 January 1969
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine
- Vol. 15 (3) , 239-244
- https://doi.org/10.1080/09553006914550421
Abstract
Non-toxic concentrations (3 × 10−6 M) of acrifavine depress the unscheduled DNA-synthesis in G1 HeLa cells at low ultra-violet (u.v.) doses (< 50 ergs/mm2), but not at higher doses. Moreover, these drug concentrations have little effect on survival at u.v. doses where the depression of unscheduled DNA-synthesis is greatest.Keywords
This publication has 10 references indexed in Scilit:
- Defective Repair Replication of DNA in Xeroderma PigmentosumNature, 1968
- Radiation Stimulated Incorporation of Thymidine into the DNA of Human LymphocytesNature, 1968
- Repair Replication in HeLa Cells after Large Doses of X-irradiationNature, 1967
- Differential effects of acriflavine and caffeine on various ultraviolet-irradiated Escherichia coli strains and T1 phageMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1967
- Effect of 5-bromodeoxyuridine on nucleic acid and protein synthesis and viability in HeLa cellsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1967
- RADIATION-STIMULATED DNA SYNTHESIS IN CULTURED MAMMALIAN CELLSThe Journal of cell biology, 1966
- Ribonucleic Acid Synthesis in Synchronously Dividing Populations of HeLa CellsNature, 1965
- Quantitation of Cellular Radiobiological ResponsesAnnual Review of Nuclear Science, 1964
- Buffers of Low Ionic Strength for Spectrophotometric pK DeterminationsAustralian Journal of Chemistry, 1963
- Photochemistry of Nucleic Acids and Their ConstituentsPublished by Elsevier ,1960