Cytokine Production in Patients with Mite-Sensitive Bronchial Asthma

Publisher Website
Google Scholar
Abstract
We examined the eosinophil viability-enhancing activity (EVEA) of peripheral blood mononuclear cells (PBMNCs) obtained from mite-sensitive bronchial asthma (BA) and normal control subjects. Mite concentrations of 1 and 10 μg/ml significantly increased EVEA in BA patients as compared with normal controls (p < 0.05 and p < 0.05, respectively). The level of IFN-γ in PBMNC culture supernatants was higher in BA patients than in normal controls. Dexamethasone, cyclosporin A and FK506 significantly inhibited EVEA in BA patients (p < 0.05 to p < 0.001).

This publication has 0 references indexed in Scilit: