Virus‐associated haemophagocytic syndrome: further evidence for a T‐cell mediated disorder

Abstract
A 16‐year‐old youth with life‐threatening virus‐associated haemophagocytic syndrome (VAHS) responded remarkably to treatment with cyclosporin A during two periods of active disease, the second of which was due to non‐compliance with treatment. Our clinical observations support the hypothesis that VAHS is cytokine driven as a result of an aberrant T‐cell response to infection.