Senile Lentigo
- 1 February 1963
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 87 (2) , 197-207
- https://doi.org/10.1001/archderm.1963.01590140059010
Abstract
Ninety per cent of elderly persons were found to have hyperpigmented macules compatible with a clinical diagnosis of senile lentigo. The morphology and distribution of these lesions are discussed. The incidence of senile lentigo increases with age and is related to the degree of senile change in the skin. The histopathology of senile lentigo is discussed. An increase in the number of melanocytes was confirmed by direct counting in dopa-treated epidermis. Lesions clinically indistinguishable from senile lentigines may show only hyperpigmentation of the epidermis histologically. Ephelides, junctional naevi, and seborrheic keratoses may present identical clinical appearances to senile lentigo but can be distinguished by histological examination. Chronic exposure to sunlight is an important etiological factor in the development of senile lentigo.Keywords
This publication has 4 references indexed in Scilit:
- A Study of the Epidermal Clear Cells with Special Reference to their Relationship to the Cells of Langerhans11From the Detroit Institute of Cancer Research, Detroit, Michigan, (William L. Simpson., M.D., Scientific Director); and the Department of Dermatology, Wayne State University College of Medicine, Detroit, Michigan. (Hermann Pinkus, M.D., Acting Chairman.)Journal of Investigative Dermatology, 1959
- Melanocyte Distribution in Forearm Epidermis of Freckled Human Subjects1Journal of Investigative Dermatology, 1957
- Quantitative and Qualitative Data on the Pigment Cells of Adult Human Epidermis1Journal of Investigative Dermatology, 1957
- A study of the branched cells of the mammalian epidermis with special reference to the fate of their division productsPhilosophical Transactions Of The Royal Society B-Biological Sciences, 1953