Embryonal Rhabdomyosarcoma of the Genitourinary Organs

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Abstract
Fourteen patients with embryonal rhabdomyosarcoma of the genitourinary organs treated with combined modality therapy are reported. Six patients with paratesticular lesions are free of tumor 7-72 mo. (mean 44) after diagnosis, while 6 of 8 with pelvic lesions are free of tumor 18-132 mo. (mean 61) following diagnosis. Two patients died of metastases. Overall, 2-yr survival free of relapse was obtained in 9 of 11 patients (81%). Of 4 patients with pelvic lesions who were treated with primary radiation-chemotherapy without exenteration, 3 were managed successfully but 1 required urinary diversion for vesical fibrosis. Current concepts in the management of embryonal rhabdomyosarcoma are discussed.