Influence of Xylitol on Demineralization of Enamel

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Abstract
In this paper the influence of xylitol on the progress of the demineralization front in enamel is described and discussed. Xylitol reduces enamel demineralization; the influence can be observed mainly at relatively high xylitol contents in solution. Autoradiography with 14C-labelled xylitol shows that xylitol penetrates fast in demineralized enamel. Most likely xylitol inhibits acid dissolution of enamel by interfering with the transport of dissolved enamel from the lesion to the bulk solution (by lowering the diffusion coefficients of calcium and phosphate ions). The results may be of practical interest for the use of xylitol in, e.g., toothpastes or chewing gums.

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