Tuberculin Negative?
- 17 February 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 286 (7) , 373-374
- https://doi.org/10.1056/nejm197202172860712
Abstract
Unexpected numbers of tuberculous patients with negative tuberculin reactions were described by Holden et al.1 in a recent issue of the Journal. Tested with several different PPD products, each used at the 5-TU (intermediate) dosage level, 17 per cent of some 115 patients with bacteriologically confirmed diagnoses of pulmonary tuberculosis failed to respond with a positive reaction to a product containing the anti-adsorbent material Tween-80, and an alarming 49 per cent to a reconstituted tableted product. Some, but by no means all, of these negative reactions could be accounted for by "extenuating clinical circumstances, such as old age, debility . . .Keywords
This publication has 2 references indexed in Scilit:
- Frequency of Negative Intermediate-Strength Tuberculin Sensitivity in Patients with Active TuberculosisNew England Journal of Medicine, 1971
- Disparity of Potency between Stabilized and Nonstabilized Dilute Tuberculin Solutions1American Review of Respiratory Disease, 1971