Mechanism-based Suppression of Dideoxynucleotide Resistance by K65R Human Immunodeficiency Virus Reverse Transcriptase Using an α-Boranophosphate Nucleoside Analogue

This publication has 34 references indexed in Scilit:

• In Vitro Selection of Mutations in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase That Decrease Susceptibility to (−)-β- d -Dioxolane-Guanosine and Suppress Resistance to 3′-Azido-3′-Deoxythymidine
  Antimicrobial Agents and Chemotherapy, 2000
• Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase
  Journal of Biological Chemistry, 2000
• Resistance Profile of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitor Abacavir (1592U89) after Monotherapy and Combination Therapy
  The Journal of Infectious Diseases, 2000
• Synthesis and Separation of Diastereomers of Ribonucleoside 5‘-(α-P-Borano)triphosphates
  The Journal of Organic Chemistry, 1998
• Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC
  Biochemistry, 1997
• In vitro selection and molecular characterization of human immunodeficiency virus type 1 with reduced sensitivity to 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA)
  Antiviral Research, 1996
• The K65R Mutation Confers Increased DNA Polymerase Processivity to HIV-1 Reverse Transcriptase
  Published by Elsevier ,1996
• Slow Rate of Phosphodiester Bond Formation Accounts for the Strong Bias that Taq DNA Polymerase Shows against 2‘,3‘-Dideoxynucleotide Terminators
  Biochemistry, 1996
• Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation
  Biochemistry, 1992
• MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
  Journal of Applied Crystallography, 1991