Abstract
The data in these papers represent a continuation of the work published in 1924,1 including a follow-up study over a period of from five to six years. Some of the patients originally studied were dropped because they had discontinued hospitalization, and others were substituted. Table 1 therefore serves to reconcile the old and new numbers, each number always indicating the same patient. The general plan of study was to investigate by laboratory and clinical methods the various body systems (e. g., circulatory, digestive, ductless glandular, etc.), to draw tentative conclusions in regard to each system and finally to correlate the observations. A review of the literature was made after this work was completed. The cooperation of a specially trained nursing staff and the use of a locked ward and mimeographed forms for the accurate recording of observations were indispensable for the completion of these studies as they now stand. Nearly

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