Pharmacokinetic Optimisation of Opioid Treatment in Acute Pain Therapy
- 1 September 1997
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 33 (3) , 225-244
- https://doi.org/10.2165/00003088-199733030-00005
Abstract
Traditionally, opioids have been administered as fixed doses at fixed dose intervals. This approach has been largely ineffective. Patient-controlled analgesia (PCA) and upgraded traditional...Keywords
This publication has 69 references indexed in Scilit:
- In vivo relationships between the cerebral pharmacokinetics and pharmacodynamics of thiopentone in sheep after short-term administrationJournal of Pharmacokinetics and Biopharmaceutics, 1996
- Postoperative pain management — beyond basicsCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 1996
- Patient-controlled analgesia compared with intramuscular injection of analgesics for the management of pain after an orthopaedic procedure.Journal of Bone and Joint Surgery, 1995
- Patient-Controlled AnalgesiaClinical Pharmacokinetics, 1993
- Reduction of post-operative morbidity following patient-controlled morphineCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 1990
- Narcotic Pharmacokinetics and Dynamics: The Basis of Infusion ApplicationsAnaesthesia and Intensive Care, 1987
- KINETICS OF C-11-LABELED OPIATES IN THE BRAIN OF RHESUS-MONKEYS1984
- Patient-controlled Analgesic Therapy, Part IIClinical Pharmacokinetics, 1982
- Multiple intramuscular injections: A major source of variability in analgesic response to meperidinePain, 1980
- THE OPTIMAL DOSE OF MORPHINEJAMA, 1954