Aerosol Immunization of Humans with Inactivated Parainfluenza Type 2 Vaccine
- 3 December 1970
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 283 (23) , 1250-1253
- https://doi.org/10.1056/nejm197012032832303
Abstract
The antibody response was compared in 40 volunteers who were immunized with parainfluenza Type 2 vaccine, either subcutaneously or by aerosol, and in 16 controls. The neutralizing-antibody response in respiratory secretions was of greater magnitude in the aerosol group than in the other groups. In both the aerosol and the subcutaneous groups there was a significant rise in serum antibody. The respiratory-secretion antibody was found in the IgA class.Keywords
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