International Clone of Neisseria meningitidis Serogroup A with Tetracycline Resistance Due to tet (B)

Abstract
Thirteen Neisseria meningitidis clinical isolates from Africa, Asia, and the United States for which the tetracycline MICs were elevated (≥8 μg/ml) were examined for 14 recognized resistance genes. Only the drug efflux mechanism encoded by tet (B) was detected. All isolates were in serogroup A, belonged to complex ST-5, and were closely related by pulsed-field gel electrophoresis analysis.