Morphologische Untersuchungen des Urothels nach Einwirkung intensiver Nanosekunden-Laserpulse

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Abstract
The energy of a Nd-YAG laser (1,064 nm wave length, 8 ns pulse duration) was used to irradiate the urothelium of the ureter or bladder and kidney parenchyma in pigs. Single pulse energy was 50–120 mJ with a 20-Hz repetition rate. The horizontal laser beam was reflected 90° down by a 100% mirror and with a specially designed apparatus focussed on the surface of the tissue. Laser light from a quartz glass fiber was also focussed directly onto the tissue. Urothelium and kidney parenchyma were irradiated in 7 pigs. Tissue samples were examined histologically and raster electron microscopically 2, 4, 8 and 12 days after irradiation. No macroscopic lesion could be found. Maximum energy caused a small cone of 40 µm depth. No thermic effects or necrosis resulted, so that no harm is to be expected with unintentional irradiation.

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