Conventional and rapid MR imaging of the liver with Gd-DTPA.

Publisher Website
Google Scholar
Abstract
Twenty-three patients with malignant hepatic tumors underwent magnetic resonance (MR) imaging before and after intravenous administration of gadolinium-diethylene-triaminepentaacetic acid (DTPA). Two different doses were used, 0.1 mmol/kg and 0.2 mmol/kg. The larger dose proved to be more effective than the smaller dose. The signal-enhancement-to-noise ratio was significantly larger in the tumor than in the liver (2.alpha. .ltoreq. .05). In a moderately T1-weighted spin echo (SE) sequence (SE 400/30) (repetition time [TR] msec/echo time [TE] msec), the tumor was better defined 6 minutes after administration of Gd-DTPA. More strongly T1-weighted sequences.sbd.that is, SE 200/20 and inversion recovery 1,500/35/400 (TR msec/Te msec/inversion time, msec).sbd.showed significantly worse contrast between tumor and liver (signal-difference-to-noise ratio [SD/N]) 10 and 15 minutes after administration (2.alpha. .ltoreq. .05). On the other hand, the low SD/N in the rapid MR imaging sequence was significantly improved (2.alpha. .ltoreq. .05). The most important indications for administration of Gd-DTPA in diagnosing hepatic tumors are the presentation of perfusion conditions and contrast optimization in rapid MR images.

This publication has 0 references indexed in Scilit: