Comparative Toxicology of the Pyrethroid Insecticides

Abstract
Synthetic pyrethroid insecticides are photostable analogs of the natural pyrethrins of botanical origin. Their structures range from very similar to the original (e.g., allethrin, Fig. 1) to highly dissimilar compounds (e.g., flucythrinate, Fig. 1). Directed synthesis by groups in Japan (Sumitomo Chemical Co.) and England (NRDC) resulted in very potent insecticides and a commercial success for the synthetic pyrethroids.

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