Highly Stereoselective Synthesis of Novel α-Haloenamides via a Mild and Efficient Hydrohalogenation of Ynamides
- 5 April 2003
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (9) , 1547-1550
- https://doi.org/10.1021/ol0300266
Abstract
A highly stereoselective preparation of novel chiral (E)-α-haloenamides under mild conditions utilizing magnesium halide salts is described. This unexpected mild and efficient hydrohalogenation reaction highlights another synthetic utility of ynamides.Keywords
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