Hepatoprotective Activity of Polyphenolic Compounds from Cynara scolymus Against CCl4 Toxicity in Isolated Rat Hepatocytes
- 1 July 1987
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 50 (4) , 612-617
- https://doi.org/10.1021/np50052a004
Abstract
The hepatoprotective activity against CCl4 toxicity in isolated rat hepatocytes of some polyphenolic compounds, such as cynarin, isochlorogenic acid, chlorogenic acid, luteolin-7-glucoside, and two organic acids, caffeic and quinic, from Cynara scolymus, is tested. Only cynarine and, to a lesser extent, caffeic acid showed cytoprotective action. The possible relationship between the molecular structure and the protective effect found is discussed.This publication has 7 references indexed in Scilit:
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