Stereoselective nucleophilic substitution of 6-methoxy-1-methoxycarbonylpipecolate: enantioselective synthesis of (+)-sedamine from L-lysine

Abstract
Amidoalkylation 6-methoxy-1-methoxycarbonylpipecolate (4) with several nucleophiles gave 2,6-cis 6-substituted pipecolates, stereoselectively.

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