Systemic Amyloidosis in Mice Inoculated with Lyophilized Candida Cells
- 1 June 1975
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 11 (6) , 1371-1374
- https://doi.org/10.1128/iai.11.6.1371-1374.1975
Abstract
Injection of lyophilized Candida albicans or C. parapsilosis cells induced amyloidosis in outbred CFW mice. The disease process was irreversible, and a significant number of animals died of systemic amyloidosis within 400 days after the last treatment. The techniques described may represent a model system for the study of systemic amyloidosis.Keywords
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