Sialic Acid and the Microheterogeneity of Human Serum Ferritin
- 1 March 1980
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 58 (3) , 259-262
- https://doi.org/10.1042/cs0580259
Abstract
Ferritin was partially purified from the serum of patients with idiopathic hemochromatosis. Incubation with neuraminidase of this partially purified serum ferritin eliminated much of the microheterogeneity of the protein so that only ferritin of isoelectric point approximately 5.8 was present. There was no change in the total amount of ferritin present (measured immunologically) or in the percentage of ferritin binding to concanavalin A. Incubation of liver, spleen or heart ferritin with neuraminidase did not change the isoelectric focusing patterns.This publication has 1 reference indexed in Scilit:
- The purification and properties of ferritin from human serumBiochemical Journal, 1976