EFFECT OF ATROPINE ON THE DECAY OF MINIATURE END‐PLATE CURRENTS AT THE FROG NEUROMUSCULAR JUNCTION
Open Access
- 1 January 1976
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 56 (1) , 111-113
- https://doi.org/10.1111/j.1476-5381.1976.tb06965.x
Abstract
The effect of atropine on the time constant of decay (τ) of miniature end‐plate currents was investigated. The atropine‐induced shortening of τ was accompanied by a reduction in the voltage‐sensitivity of τ. This effect of atropine was reversible and dose‐dependent, the voltage sensitivity being abolished with high concentrations of atropine (2.5 × 10−5 m).Keywords
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